Impaired magnesium resorption

Magnesium deficiency can also occur if the absorption of magnesium by the intestine is impaired. This can be caused by various diseases or the use of certain medications.

Magnesium absorption is impaired in patients with irritable bowel syndrome, diarrhoeal diseases or chronic inflammatory bowel diseases such as Crohn's disease. As a result, the body does not absorb enough magnesium and symptoms of a deficiency may occur. Genetic defects can also disrupt magnesium absorption.

The regular use of medication can also have a negative effect on magnesium levels. For example, magnesium, fluorides and tetracycline antibiotics can influence each other in terms of absorption.

The long-term use of acid blockers (also called proton pump inhibitors or PPIs) such as omeprazole or pantoprazole for treating acid reflux and heartburn can lead to severe magnesium deficiency and other problems due to impaired magnesium absorption. This is why the patient information leaflets of these medicinal products contain a warning about magnesium deficiency.

Good to know:

People regularly taking acid blockers should watch for symptoms of magnesium deficiency (such as leg cramps or tension) and take a high-quality magnesium product. In such cases, products containing organic magnesium citrate (such as Magnesium Diasporal 300 mg) have proven effective. Unlike inorganic magnesium compounds, magnesium citrate does not require stomach acid to be absorbed by the body. It can therefore prevent magnesium deficiency due to acid blockers.