Magnesium and medication

Gastric acid blockers can result in magnesium deficiency

A long-term therapy with gastric acid blockers (protone pump inhibitors such as omeprazole, pantoprazole) as treatment for acid reflux and indigestion, can result in a severe magnesium deficiency, among other symptoms due to the magnesium intake being impaired. Corresponding warning instructions are provided with the medications concerned. When taking gastric acid blockers on a regular basis, please therefore watch out for the symptoms of a magnesium deficiency (e.g. calf cramps, tension) and take a high quality magnesium preparation additionally. This enables you to prevent a magnesium deficiency being caused by the above medications.


Take a preparation containing an organic magnesium citrate, as magnesium citrate does not requires gastric acid for the releasing of the magnesium and can be absorbed by the body directly. This enables the symptoms of a magnesium deficiency to be treated effectively.

Our recommendation:

Magnesium-Diasporal® 300 mg, granules for oral solution. The only pharmaceutical drug with pure magnesium citrate in the form it exists in the body as an element, making it kind to the body and fast acting.

Magnesium-Diasporal® 300 mg, granules (active ingredient: magnesium citrate). Therapeutic indication: Treatment and prevention of magnesium deficiency. Contains sucrose (sugar) and sodium. For risks and side effects, please consult your doctor or pharmacist. Protina Pharmazeutische GmbH, D-85737 Ismaning

Important: Use a magnesium supplement with gentle-acting magnesium citrate.

Magnesium citrate can be absorbed directly by the body and does not need gastric acid for the release of magnesium. Thus, symptoms of a magnesium deficiency can be readily treated. Our recommendation: Magnesium-Diasporal® 300, granules for oral solution. The only pharmaceutical with pure magnesium citrate in the form in which it occurs as a building block in the body.

Loss of magnesium because of dehydrating agents and laxatives

Dehydrating agents (diuretics), which are employed against fluid retention in the body (oedemas), cardiac insufficiency and high blood pressure, lead to an increased excretion of magnesium via the kidneys and therefore promote magnesium deficiency. This also applies to laxatives. Hence, attention should be paid to a sufficient magnesium supply if these preparations are taken over a longer time.

Magnesium and calcium – keep a distance

With the simultaneous intake of magnesium and calcium (e.g. 300 mg magnesium and 1000 mg calcium), one of the mineral compounds can hamper the absorption of the other. Therefore, we recommend that two to three hours be left between the intakes of high dosages of magnesium and calcium supplements. Recommendation: Take calcium in the morning and then magnesium in the evening. This does not apply to combinations with lower dosages.


Fibromyalgia aka fibre muscle pain is a serious chronic, non-inflammatory and as-yet incurable condition characterised by widespread pain of the muscles, joints and back as well as tenderness to pressure. Accompanying symptoms include fatigue, sleep disturbances, stiffness in the morning, poor concentration and motivation and a host of other signs.

Scientific research has shown that fibromyalgia patients have lower magnesium levels than healthy persons. Since magnesium plays a direct role in muscle and nerve function, a magnesium deficiency can adversely affect the course of the disease.


We recommend to allow 2 to 3 hours between taking the magnesium supplement and your other medicines to reduce the possibility of interaction